Panama 5-Day Tours & Itineraries

Explore 5 trips designed by local kimkim specialists to get ideas for your trip to Panama.
See our itineraries below or read our guide to the best 5-day trips in Panama.
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Relax as you sail around the Caribbean waters of Panama's San Blas Islands
Map of Sailing Escape to Panama's San Blas Islands - 5 Days
Sailing Escape to Panama's San Blas Islands - 5 Days

Set your course for the San Blas Islands on this five-day Caribbean sailing getaway. Fly into Panama City and spend a day exploring the dynamic capital of skyscrapers and cobblestones. Then it's time to board a luxury catamaran, your home for the next three nights as you sail between the palm-fringed islands of this unspoiled archipelago—swimming in shallow turquoise waters, snorkeling above a shipwreck, and experiencing the island life and culture of the Indigenous Guna people along the way.

Dive into the history and cuisine of Panama City's Casco Antigua district
Map of History & Nature in Panama City & Bocas del Toro - 5 Days
History & Nature in Panama City & Bocas del Toro - 5 Days

This five-day itinerary takes you from cosmopolitan Panama City to the archaeological sites of Panama Viejo and the Caribbean jungles of Isla Bastimentos. Begin by touring food markets and tasting traditional dishes before wandering the centuries-old Panama Viejo, a historic city where the Spanish settled in the 1500s. Witness the world-renowned Panama Canal in action before spending your last few days exploring the nearby Bocas del Toro islands and snorkeling among ocean life.

Experience some of Panama's diverse culture on this five-day trip
Map of Culture, History & Nature in Panama City & the Caribbean Coast - 5 Days
Culture, History & Nature in Panama City & the Caribbean Coast - 5 Days

This five-day exploration of Panama's culture, history, and nature begins among the historic cobblestone streets of the capital and along the famous Panama Canal. Take a river cruise down the Río Chagres and visit a local Embera village before heading to the relaxed fishing village of Portobelo—once an integral Spanish port—to experience the best of the Panamanian Caribbean through dance, cuisine, and quality beach time.

Bask in the colorful tropical paradise of Panama's Pearl Islands
Map of Panama City & Pearl Islands Getaway - 5 Days
Panama City & Pearl Islands Getaway - 5 Days

Escape to Panama for five days of culture and relaxation between the bustling capital and the white-sand beaches of the Pearl Islands. Visit a national park on the shores of the iconic Panama Canal, search for whales off the coast of Isla Contadora, island hop among the 200 islands of the Pearl archipelago, and savor diverse Panamanian flavors in the historic Casco Antiguo.

Admire colonial churches and colorful historic architecture in Panama City's historic center
Map of Culture, History & Gastronomy in Taboga Island & Panama City - 5 Days
Culture, History & Gastronomy in Taboga Island & Panama City - 5 Days

Get a quick taste of Panama's many charms with this captivating five-day island-and-city getaway. Start with relaxation on the tropical island of Taboga, brimming with sandy shores, colonial architecture, and exotic flavors. Then it's on to the modern skyscrapers and historic neighborhoods of Panama City, where you'll visit fascinating sites like the Panama Canal and the Biomuseo and embark on a flavorful food tour through the atmospheric Casco Antiguo.

Other durations: 5 days · 7 days · 8 days · 10 days