With three weeks, you can see 5-10 regions of Argentina and Chile, depending on your pace. First-time visitors can see famous sites in Buenos Aires and Santiago, sample wine in Mendoza, and visit Iguazú Falls. Outdoorsy travelers will enjoy hiking at Perito Moreno Glacier, kayaking to the Marble Caves, and tackling a trek at Torres del Paine National Park. Aspiring chefs, wine lovers, and foodies can take a culinary walk in Buenos Aires, tour vineyards in the Uco Valley, and join a cooking class in Santiago.

Itinerary #1: Epic Argentina & Chile Discovery: Buenos Aires, Iguazú Falls, Patagonia & the Lake District

This highlights itinerary is a match for adventurous travelers who enjoy hiking, bird watching, and some self-directed experiences. You'll tour Buenos Aires at your own pace, visit Iguazú Falls, take a self-guided hike in El Chaltén, see Perito Moreno Glacier by boat, trek in Torres del Paine National Park, search for wildlife in Queulat National Park, kayak to the Marble Caves, hike in Vicente Pérez Rosales National Park, go bird-watching in Alerce Andino National Park, and more. This trip is fast-paced and includes several flights, so it's best for those who want to make the most of their time and pack in a lot of activities.

Look out over Mount FitzRoy on one of many memorable Patagonian hikes
View Mount Fitz Roy on one of many memorable Patagonian hikes
Day Highlights Overnight
Day 1 Arrive in Buenos Aires (Argentina), Optional Activities Buenos Aires
Day 2 Free Day in Buenos Aires Buenos Aires
Day 3 Fly to Puerto Iguazú, Explore Iguazú Falls (Brazilian Side) Puerto Iguazú
Day 4 Explore Iguazú Falls (Argentine Side) Puerto Iguazú
Day 5 Fly to El Calafate, Transfer to El Chaltén El Chaltén
Day 6 Self-Guided Hike in El Chaltén El Chaltén
Day 7 Transfer to El Calafate El Calafate
Day 8 Perito Moreno Glacier Tour El Calafate
Day 9 Transfer to Torres del Paine National Park (Chile) Torres del Paine
Day 10 Day Hike in Torres del Paine Torres del Paine
Day 11 Transfer to Punta Arenas Punta Arenas
Day 12 Fly to Coyhaique via Puerto Montt Coyhaique
Day 13 Full-Day Queulat National Park Tour Coyhaique
Day 14 Transfer to Puerto Río Tranquilo Puerto Río Tranquilo
Day 15 Marble Caves Kayak Tour Puerto Río Tranquilo
Day 16 Fly to Puerto Montt, Transfer to Puerto Varas Puerto Varas
Day 17 Day Trip to Vicente Pérez Rosales National Park Puerto Varas
Day 18 Trekking in Alerce Andino National Park Puerto Varas
Day 19 Transfer to Pucón Pucón
Day 20 Lagunas Andinas Trekking Pucón
Day 21 Fly to Santiago, Depart  


Ease into your trip with free time in Buenos Aires (Argentina) to visit Puerto Madero, the Teatro Colón opera house, and other sites at your own pace. Then, jet off to Puerto Iguazú to experience both the Brazilian and Argentine sides of the thundering Iguazú Falls before catching a flight south to El Calafate, the gateway to Los Glaciares National Park. Here, you'll hike in El Chaltén and take a boat tour to the Perito Moreno Glacier. Next, your driver will transfer you to Torres del Paine National Park in Chile, where you can choose a half-day or full-day trek, then continue to Punta Arenas for your flight to the Lake District.

Take a guided hike through lenga forests, passing fjords and waterfalls and searching for Andean armadillos and other wildlife in Queulat National Park before retiring to your hotel in Coyhaique. Your driver will transfer you to Puerto Río Tranquilo for a kayaking excursion to the Marble Caves on Day 15 before your flight to Puerto Montt. With a few days in Puerto Varas, you'll hike in Vicente Pérez Rosales National Park and go bird-watching in Alerce Andino National Park. Finally, board a bus to Pucón, where you'll cap off the trip with a forest walk alongside secluded lakes and lagoons on the Mamuil Malal Pass. Learn more

Itinerary #2: Wonders of Chile & Argentina

Travelers who like a combination of popular spots and adventures off the beaten path will enjoy this itinerary. You'll see another side of Santiago on an alternative tour, take a sunrise hot-air balloon ride over the Atacama Desert, admire glaciers on a Laguna San Rafael boat tour, and visit penguins at Isla Magdalena. You'll then trek in Torres del Paine, hike glaciers near El Chaltén and El Calafate, go on an off-roading 4WD adventure and canoe excursion in Tierra del Fuego National Park, and end with a bike tour and tango show in Buenos Aires.

Hike across the largest advancing glacier on Earth at Perito Moreno
Hike across one the world's largest advancing glaciers at Perito Moreno
Day Highlights Overnight
Day 1 Arrive in Santiago (Chile), Alternative City Tour Santiago
Day 2 Fly to Atacama Desert, Valley of the Moon Tour San Pedro de Atacama
Day 3 Sunrise Balloon Ride, Lagoons & Salt Flats Tour San Pedro de Atacama
Day 4 Tour Tatio Geysers & Baltinache Lagoons San Pedro de Atacama
Day 5 Fly to Balmaceda via Santiago Puerto Río Tranquilo
Day 6 Marble Caves Kayak Tour Puerto Río Tranquilo
Day 7 San Rafael & Glacier Boat Trip Puerto Río Tranquilo
Day 8 Fly to Punta Arenas Punta Arenas
Day 9 Visit Penguin Colony, Transfer to Torres del Paine Torres del Paine
Days 10-11 Explore Torres del Paine National Park Torres del Paine
Day 12 Transfer to El Calafate (Argentina) El Calafate
Day 13 Perito Moreno Glacier Hike El Calafate
Day 14 Transfer to El Chaltén El Chaltén
Day 15 Hike to Laguna de Los Tres El Chaltén
Day 16 Transfer to El Calafate, Fly to Ushuaia Ushuaia
Day 17 Trekking & Canoeing in Tierra del Fuego National Park Ushuaia
Day 18 Tierra del Fuego Off-Road Adventure Ushuaia
Day 19 Fly to Buenos Aires, Optional Activities Buenos Aires
Day 20 Buenos Aires Bike Tour, Dinner & Tango Show Buenos Aires
Day 21 Depart Buenos Aires  


See lesser-known spots in Santiago (Chile) on an alternative walking tour before flying to Calama for your Atacama Desert adventures. Spend three days immersed in the desert with a sunset tour in the Valley of the Moon, a sunrise balloon ride, and visits to salt flats, Tatio Geysers, and the Hidden Lagoons of Baltinache. Then, you'll fly to the Aysén region of Patagonia, where you'll kayak through marble caves and admire glaciers on a Laguna San Rafael boat tour. Next, fly to Punta Arenas and head to Isla Magdalena to observe the penguins before your driver transfers you to Torres del Paine National Park. 

Enjoy leisurely walks to lakes and glaciers in Torres del Paine National Park, or opt for more challenging hiking and scrambling. On Day 12, your driver will bring you to El Calafate in Argentina, where you'll hike the Perito Moreno Glacier and trek the famous trail to Laguna de los Tres, stopping at viewpoints for Fitz Roy, Piedras Blancas Glacier, and more. Then, fly to Ushuaia for off-roading 4WD adventures and canoeing in Tierra del Fuego National Park. Your last stop is Buenos Aires, where you'll explore the neighborhoods by bike and celebrate with a traditional tango show and dinner before departure. Learn more

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Itinerary #3: Argentina & Chile Panorama: Buenos Aires, Tierra del Fuego, Patagonia & Santiago

Slowing the pace down, this itinerary is ideal for those eager to experience cuisine and culture in addition to outdoor activities. Start with a tasting tour, attend a tango show, and join a dinner party in Buenos Aires. Then, walk with penguins in Ushuaia, hike to Los Cóndores, take a nautical safari in Los Glaciares National Park, trek in Torres del Paine National Park, tour the Chilean Patagonia glaciers, cycle around Santiago, go wine tasting in the Casablanca Valley, and learn the secrets of Chilean cuisine in a cooking class. You'll also have the chance to take a day trip to a UNESCO-listed historic town in neighboring Uruguay. 

A fisherman's cottage near the coast of Tierra del Fuego
Enjoy coastal views near Tierra del Fuego
Day Highlights Overnight
Day 1 Arrive in Buenos Aires (Argentina), Dinner & Tango Show  Buenos Aires
Day 2 City Tour & Palermo Food Walk Buenos Aires
Day 3 Day Trip to Colonia del Sacramento (Uruguay) Buenos Aires
Day 4 Buenos Aires Free Day, Culinary Experience Buenos Aires
Day 5 Fly to Ushuaia, Optional Activities Ushuaia
Day 6 Half-Day National Park Hike & Train Ride Ushuaia
Day 7 Day Trip to Isla Martillo & Penguin Walk Ushuaia
Day 8 Half-Day Trek to Laguna Esmeralda Ushuaia
Day 9 Fly to El Calafate El Calafate
Day 10 Perito Moreno Glacier Excursion, Nautical Safari El Calafate
Day 11 El Chaltén Viewpoints & Waterfalls Hike El Calafate
Day 12 Estancia Visit & Perito Moreno Boat Tour El Calafate
Day 13 Transfer to Puerto Natales (Chile), Optional Activities Puerto Natales
Day 14 Day Trip to Torres del Paine National Park Puerto Natales
Day 15 Day Trip to Balmaceda & Serrano Glaciers Puerto Natales
Day 16 Full-Day Hike to Base Torres Puerto Natales
Day 17 Fly to Santiago Santiago
Day 18 Santiago City Bike Tour Santiago
Day 19 Day Trip to Valparaíso & Casablanca Valley Santiago
Day 20 Chilean Cooking Class Santiago
Day 21 Depart Santiago  


Experience Argentine culture and cuisine with a tasting tour and a tango show on arrival in Buenos Aires. Then, take the ferry to Colonia del Sacramento, Uruguay, for a walking tour of the UNESCO-listed colonial town. Return to Buenos Aires for a culinary experience complete with an empanada-making workshop followed by a dinner party before flying to Ushuaia. At the "End of the World," you'll hike in Tierra del Fuego National Park, take a penguin walk on Isla Martillo, and see hanging glaciers on your trek to Laguna Esmeralda. Next, you'll fly to El Calafate, the gateway to the Southern Patagonian Ice Field.

Admire the massive Perito Moreno Glacier from various viewpoints and take a nautical safari in Los Glaciares National Park before continuing to El Chaltén for a hike to Los Cóndores followed by a trek to the Salto del Chorillo waterfall. Board a bus to Puerto Natales (Chile), your base, for four days of outdoor adventures that include hikes in Torres del Paine National Park, a boat tour to glaciers in Chilean Patagonia, and a full-day hike to Mirador Las Torres. Finally, you'll fly to Santiago to wrap up your trip with a cycling tour, wine tasting in the Casablanca Valley, and a Chilean cooking class. Learn more

Itinerary #4: Ultimate Argentina & Chile Tour: Cities, Waterfalls, Wine & Deserts

Wine lovers will appreciate the opportunities to sample some of the best Argentine and Chilean wines on this itinerary that forgoes Patagonia and focuses on highlights of the north. You'll attend a dinner party and wine pairing in Buenos Aires, drink Argentine wine with dinner at a traditional barbecue at a ranch near San Antonio, visit the famous vineyards of Mendoza, and tour Chile's Colchagua Valley wine region—in addition to stargazing and soaking in hot springs in the Atacama Desert and visiting popular sites in Buenos Aires, Santiago, and Iguazú.

Go on wine tours and learn about life as a  gaúcho among other adventures in Argentina
Learn about the gaúcho life on a day trip to a Argentine ranch
Day Highlights Overnight
Day 1 Arrive in Buenos Aires (Argentina), Dinner & Tango Performance Buenos Aires
Day 2 City Tour & Culinary Experience Buenos Aires
Day 3 Day Trip to San Antonio & Estancia El Ombú Buenos Aires
Day 4 Free Day in Buenos Aires, Palermo Food Walk Buenos Aires
Day 5 Fly to Puerto Iguazú Puerto Iguazú
Day 6 Day Trip to Parque das Aves & Iguazú Falls (Brazilian Side) Puerto Iguazú
Day 7 Explore Iguazú Falls (Argentine Side) & Boat Trip Puerto Iguazú
Day 8 Fly to Mendoza, Sunset Horseback Ride Mendoza
Day 9 Uco Valley Wine Tour Mendoza
Day 10 Full-Day Aconcagua Park Tour Mendoza
Day 11 Spa Day at Termas de Cacheuta Mendoza
Day 12 Fly to Santiago (Chile) Santiago
Day 13 Santiago City Tour Santiago
Day 14 Day Trip to Valparaíso & Viña del Mar Santiago
Day 15 Colchagua Wine Valley Tour Santiago
Day 16 Fly to San Pedro de Atacama, Evening Astronomy Tour San Pedro de Atacama
Day 17 Full-Day Moon & Rainbow Valley Tour San Pedro de Atacama
Day 18 Full-Day Lagoons & Salt Flats Tour San Pedro de Atacama
Day 19 Day Trip to Tatio Geysers San Pedro de Atacama
Day 20 Fly to Santiago, Optional Activities Santiago
Day 21 Depart Santiago  


Begin in Buenos Aires, Argentina, with a city tour that includes landmarks like the Teatro Colón, a live tango show and lesson, and a dinner party. Then, head to Estancia El Ombú for a horseback ride and traditional asado (Argentine barbecue). Take a food walk around Palermo's restaurants and bars before flying to Puerto Iguazú. Visit the Brazilian side of Iguazú Falls and observe toucans and other birds at Parque das Aves before taking a boat tour of the Argentine side of the falls. Next, fly to Mendoza and embark on a sunset horseback ride, followed by a barbecue dinner complete with malbec wine. 

Spend a day touring vineyards and sipping local wines in the Uco Valley, then admire the historic sites in Aconcagua Provincial Park and soak in the thermal waters of Termas de Cacheuta. Fly to Santiago, Chile, on Day 12 for a guided city tour, a day trip to artsy Valparaíso, and a wine tour in Colchagua Valley. Spend your final days in the Atacama Desert—stargazing in the Altiplano, admiring Las Tres Marias salt sculptures and the vibrant colors of Rainbow Valley, visiting scenic lagoons and salt flats, witnessing the Tatio Geysers, and relaxing in geothermal pools—before returning to Santiago for departure. Learn more

Itinerary #5: Wine Country, Deserts & Mountains of Argentina & Chile

Spending most of your time in Argentina, this alternate highlights itinerary is a great choice for first-time visitors interested in experiencing a mix of historic sites, city tours, dramatic landscapes, wine tastings, and outdoor adventures. You'll tour the neighborhoods of Buenos Aires and attend a tango show, savor world-class wines in Mendoza and the Uco Valley, see the iconic Iguazú Falls, red canyons of Quebrada de las Conchas, and salt flats of Salinas Grandes, visit colonial towns and an alpaca farm, and enjoy a whitewater rafting adventure. 

Visit wineries in famous regions like Mendoza
Tour wineries in well-known wine regions like Argentina's Mendoza
Day Highlights Overnight
Day 1 Arrive in Buenos Aires (Argentina), Dinner & Tango Performance Buenos Aires
Day 2 Neighborhoods Tour, Argentina Culinary Experience Buenos Aires
Day 3 Day Trip to San Antonio & Estancia El Ombú Buenos Aires
Day 4 Day Trip to Colonia del Sacramento (Uruguay) Buenos Aires
Day 5 Fly to Salta, Optional Activities Salta
Day 6 Day Trip to Cafayate Salta
Day 7 Day Trip to Cachi Salta
Day 8 Day Trip to Purmamarca & Salinas Grandes Salta
Day 9 Salta Whitewater Rafting Tour Salta
Day 10 Fly to Puerto Iguazú Puerto Iguazú
Day 11 Iguazú Falls Tour (Brazilian Side), Parque das Aves Puerto Iguazú
Day 12 Iguazú Falls Tour (Argentine Side) & Boat Trip Puerto Iguazú
Day 13 Fly to Mendoza Mendoza
Day 14 Uco Valley Wine Tour Mendoza
Day 15 Full-Day Aconcagua Park Tour Mendoza
Day 16 Spa Day at Termas de Cacheuta Mendoza
Day 17 Fly to Santiago (Chile) Santiago
Day 18 Santiago Markets City Bike Tour Santiago
Day 19 Full-Day Winery & Alpacas Tour Santiago
Day 20 Day Trip to Cajón del Maipo & El Yeso Reservoir Santiago
Day 21 Depart Santiago  


On arrival, you'll tour the sites and neighborhoods in Buenos Aires, take in a tango performance, and learn how to prepare an Argentine meal. Then, head to Estancia El Ombú to learn about ranch life and taste traditional barbecue before crossing into Uruguay to see Colonia del Sacramento. Fly to Salta next and take a scenic ride past the red canyons of Quebrada de las Conchas en route to a torrontés wine tasting in Cafayate. On Day 7, your driver will bring you through the Lerma Valley and Los Cardones National Park to Cachi, where you'll enjoy a walk around the historic town and visit the Museo Arqueológico de Cachi.

Snap fun photos in the otherworldly landscapes of the Salinas Grandes salt flats, then zip down the Río Juramento on a whitewater rafting trip. Next, see Iguazú Falls from both the Argentine and Brazilian sides before you fly to Mendoza. You'll tour the Uco Valley wine region, visit Aconcagua Provincial Park, and unwind with a spa day at Termas de Cacheuta. On Day 17, fly to Santiago, Chile, for a cycling tour and a visit to Viña San Esteban, where you'll meet alpacas and taste malbec and carménère wines. Spend your last full day in Cajón del Maipo—hiking at El Yeso Reservoir and sampling sweets at Casa Chocolate. Learn more

More Great Argentina Itineraries

Looking for more inspiration for your trip to Argentina? Check out these other Argentina itineraries, with outdoor adventures, cultural trips, and best-of tours to hit the highlights.

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Map of 3 Weeks in Argentina & Chile - 5 Unique Itinerary Ideas
Map of 3 Weeks in Argentina & Chile - 5 Unique Itinerary Ideas