1 Week in Patagonia - 5 Luxury Itinerary Ideas

Itinerary #1: Luxury Escape to Southern Patagonia: Buenos Aires & Ushuaia

Premium wine, dazzling lakes, dramatic mountains, and vibrant cities—Patagonia has it all, and this well-rounded luxury tour immerses you in its finest. Perfect for first-time visitors with a penchant for the finer things in life, you'll spend your nights tucked in premium accommodations and your days embarking on exclusive excursions. Delight in an afternoon at the ever-so-charming Casa Gamboa Vineyard, soar over the Andes in a helicopter, visit a penguin colony, conquer world-class hikes, and more.

Welcome to Patagonia! Your luxury adventure begins in Buenos Aires, where you'll refresh at the elegant Duque Hotel Boutique & Spa before joining up with an expert guide for a city tour. The following morning, sip your way through the exceptional wines of Casa Gamboa Vineyard and stay for a multicourse lunch at its charming countryside restaurant. Then, you're off to Ushuaia—the southernmost city in the world. Here, the 5-star Cerro Alarkén Nature Reserve greets your arrival, while shortly after, a thrilling helicopter tour whisks you above Andean peaks and valleys.

The next day, glide between the rocky islets of the Beagle Channel while onboard a private sailboat and experience the richness of freshly caught and cooked seafood served at a family's home. Then, don your trail shoes for a delightful trek through native lenga trees and along mountain streams to Laguna Esmeralda. Another superb adventure awaits on Day 6, this one featuring an adrenaline-inducing 4WD journey down historic logging roads. On your final morning, shoot to Tierra del Fuego National Park to squeeze in a hike of your choosing before catching your onward flight from Ushuaia. Learn more

Itinerary #2: Active Luxury Trip to Argentine Patagonia: Buenos Aires, El Calafate & El Chaltén

Cruise past daring icebergs, raft through river canyons, and hike to mesmerizing turquoise lagoons on this active luxury adventure. Designed for travelers who seek an active escape without sacrificing comfort, this journey offers immersive activities and opulent accommodations that showcase the region's finest. Starting in Buenos Aires and staying in exquisite lodgings in both El Calafate and El Chaltén, you'll discover firsthand why Argentine Patagonia is considered a world-class destination.

Upon arriving in Buenos Aires, you'll be welcomed by a driver and whisked to the 4-star Duque Hotel Boutique & Spa. Refreshing will be easy with an on-site spa to take advantage of, then spend the rest of the evening immersed in a private empanada-cooking workshop and zipping between city highlights on a bicycle the following morning. That afternoon, it's back to the airport for a flight south to El Calafate. After a leisurely evening, a private guide will collect you for a day trip to the spectacular Perito Moreno Glacier, complete with the opportunity to boat close to its massive ice walls. 

In the second half of your adventure, you'll dive into thrilling excursions and outstanding hikes available near El Chaltén. Kick things off with an exhilarating whitewater rafting adventure down the Río de las Vueltas, then lace up your hiking boots for a challenging and highly rewarding trek to Laguna de los Tres. Additionally, navigate through lush green lenga forests to Laguna Torre and follow your guide's lead to a beautiful town overlook at Mirador de los Cóndores. Between adventures, enjoy decadent nights at Los Cerros del Chaltén boutique hotel, keeping you fully refreshed for your departing flight. Learn more

Itinerary #3: Luxury Chilean Patagonia Getaway: Outdoor Adventures & Wine Tasting

Perfectly combining urban fun with incredible hiking, this premier one-week getaway is an excellent choice for those seeking a quintessential Chilean Patagonia experience. Throughout, you'll trek beneath the rugged peaks of French Valley, marvel at panoramic vistas from Mirador Base Torre, and indulge in wine amid the serene vineyards of Casablanca Valley. Adding to the luxury, enjoy three nights at the exclusive Hotel Las Torres and savor sumptuous Patagonian barbecue.

After catching your connecting flight from Santiago to Puerto Natales, drop your bags at the renowned Singular Patagonia luxury hotel and head out for an invigorating walk along the city's promenade. The next day, continue into Torres del Paine National Park, where a charming ranch-style luxury hotel welcomes your arrival. Beyond its fine amenities, your hotel is also ideally situated at the start of the W-Trek—meaning you'll have prime access to some of the park's finest trails. Kick things off with an introductory hike, then pack your day bag for a challenging trek up to Mirador Base Torres.

Your final day in Torres del Paine National Park is also one for the memory books, with a lengthy hike into the dramatic French Valley on the agenda. Afterward, pack away your hiking gear and shift your attention to the urban wonders and mountain-backed vineyards of Santiago. While calling the extravagant Singular Santiago home, stroll the streets of the fashionable Barrio Bellavista, tuck into trendy wine bars, and join a guide for a private tour of Casablanca Valley's finest wineries. Lastly, squeeze in visits to Mercado Central and the impressive Catedral Metropolitan before catching your onward flight. Learn more

Itinerary #4: Luxury Active Chilean Patagonia: Lakes & Volcanoes

Immerse yourself in Patagonia's wild side without forgoing your creature comforts on this adventure-filled journey through Chile. Begin in Santiago, where you'll explore the natural wonders of Cajón del Maipo by day and unwind at the luxurious Singular Santiago hotel by night. Then, fly to Puerto Varas for four exceptional days of hiking, boating, and kayaking, all beneath the snowcapped Osorno volcano.

There's an abundance of thrilling activities to look forward to over the coming week, but first, in Santiago, ease any travel fatigue with a lavish spa session at the 5-star Singular Santiago. Additionally, a gourmet dinner and a leisurely city stroll ensure you're refreshed and ready for the following morning's trip to the rugged region of Cajón de Maipo, filled with short hikes to scenic viewpoints. Then, on Day 3, you're off to the Lake District's charming town of Puerto Varas. Upon arrival, drop your bags at the fabulous Casa Molino before spending the rest of the afternoon exploring independently. 

You've had a taste of Patagonia's stunning landscapes, and now it's time to lace up your trail shoes and get among them—starting with a six-hour hike along the base of Osorno volcano. The excitement continues the next day with a boat ride to Isla Chiloé on the agenda, where you'll have the opportunity to admire penguins, swans, flamingoes, and more. Then, detour to Puerto Montt for another excellent hike, this one along the Río Chaicas, and to Laguna La Poza for a kayaking adventure. Lastly, conclude your journey with a return flight to Santiago, ready for your onward travels. Learn more

Itinerary #5: Luxury Patagonia Glamping Adventure: Santiago & Torres del Paine

Crafted for those seeking overnight luxury accommodations amid nature's splendor, this weeklong escape includes four nights of chic, remote glamping. While calling the beautiful Patagonia Camp home, you'll have privileged access to the incredible glaciers, valleys, lakes, and plains of Torres del Paine National Park. Delight in activities catered to your preferences, but first, kick things off with a stay in Santiago featuring a full-day Casablanca Valley wine tour.

Your luxury-wrapped tour of Patagonia begins with a two-day stay in Santiago, the first of which you'll spend shrugging off jet lag in style. Unwind at the luxurious 5-star Singular Santiago, then slip on your walking shoes for a city highlights tour. The next day, treat yourself to an exquisite afternoon of winery hopping in the picturesque Casablanca Valley, featuring tastings at the illustrious Casa Marín and Viñedo Matetic wineries. Afterward, prepare for a memorable experience as you transfer to Patagonia Camp, renowned for its eco-friendly luxury, on the doorstep of Torres del Paine National Park.

Waking up tucked in a comfy yurt promises to be an experience you won't soon forget, and that's just the start of the epic adventures to come. Over the following days, you'll tackle a challenging 11.2 mile (18 km) trek up to Mirador Base Torres, take in the grandeur of Grey Glacier from a catamaran, and horseback ride across sweeping windswept plains. The attentive staff at Patagonia Camp are also ready to curate personalized experiences, whether you prefer kayaking, leisurely hikes, or photography tours. Yet, all too soon, you'll have to say farewell and catch your departing flight to Santiago. Learn more

More Great 1-Week Patagonia Itineraries

Looking for more inspiration for your trip to Patagonia? Check out these other one-week Patagonia itineraries, with outdoor adventures, cultural trips, and best-of tours to hit the highlights.