2 Weeks in Patagonia - 5 Luxury Itinerary Ideas

Itinerary #1: Ultimate Luxury Exploration of Patagonia: Chile to Argentina

Hike, cruise, ride horseback, and sightsee your way through Patagonia's dramatic landscapes on this luxury two-week exploration. Perfect for first-time visitors to Chile and Argentina, you'll find lavish accommodations in Torres del Paine National Park, El Calafate, and El Chaltén, which are excellent bases to tackle challenging treks and exclusive excursions catered to your liking. Additionally, delight in fine dining and privately guided tours in Santiago and Buenos Aires.

Welcome to Patagonia! Your luxury adventure kicks off in Chile's grand capital of, Santiago, where you'll elegantly shake off travel fatigue while exploring the city and strolling amid the colorful plazas of nearby towns. Next up is a four-day stay at the glamorous Patagonia Camp, tucked within Torres del Paine National Park. Here, a range of activities will be organized according to your preferences and can include a rewarding trek up to Mirador Base Torres and a Grey Glacier catamaran excursion. Afterward, continue to El Calafate and take a night to rejuvenate at the 5-star Xelena Hotel & Suites. 

Over the following two days, you'll delve deep into the awe-inspiring landscapes of Los Glaciares National Park, first during a nautical safari to Perito Moreno Glacier and second onboard a ferry cruising along the Upsala Channel. Then, venture north to El Chaltén and delight in back-to-back days of world-class hiking and decadent evenings at the scenic Aguas Arriba lodge. Your final destination is Buenos Aires, where a chef-led cooking class kicks off your stay. Afterward, check out city highlights and spend an afternoon exploring the Venetian-style village of Tigre before catching your onward flight. Learn more

Itinerary #2: Luxury Argentine Patagonia Discovery: Buenos Aires, Bariloche, El Calafate & Ushuaia

Discover the untamed and distinctly wild landscapes of Argentina on this highlights discovery itinerary. Perfect for those looking to experience the overwhelming beauty of Patagonia through the eyes of a local, you'll not just see but fish, cruise, hike, and off-road amid mighty mountains and near towering glaciers. When you're not out exploring, rejuvenate at tucked-away accommodations selected for their excellent amenities and privileged locations.

Two days based in Buenos Aires, cycling through the city's lively neighborhoods and learning about gaúcho (cowboy) culture at a working ranch provides the perfect introduction to the rhythms and flavors of Argentine life. Then, after jetting to Bariloche and refreshing at the 4-star Villa Beluno Hotel & Spa, it's time to take things up a notch. Don your trail shoes for an epic hike up to the towering peak of the Cerro Catedral massif, enjoy jaw-dropping scenery during a tour along the Seven Lakes Road, and learn the ropes of fly fishing. Next, fly to El Calafate, where the fabulous Xelena Hotel & Suites await your arrival.

Refreshed from an indulgent night at a closed-door restaurant, you'll be eager to tackle a bucket-list-worthy kayak journey near the majestic Perito Moreno Glacier, followed by a horseback ride at one of the region's most impressive working ranches. Your next destination, the southernmost city of Ushuaia, promises more fantastic full-day adventures. On board a private boat, sail to the penguin-inhabited Isla Martillo and off-road your way through the wild landscapes of Tierra del Fuego National Park. Lastly, fly to Buenos Aires and round off your adventure with lunch at the famed Don Julio. Learn more

Itinerary #3: Luxury Tour of Patagonia's National Parks: From Argentina to Chile

This well-rounded adventure through Patagonia's National Parks introduces you to the natural wonders and opulent offerings of Tierra del Fuego, Los Glaciares, and Torres del Paine. Over a memorable two weeks, you'll sail past sea lion colonies, 4WD across alpine terrain, cruise near the creaking walls of the Perito Moreno Glacier, and horseback ride under granite peaks. To top it off, upscale dinners, an exclusive tango show, and a Colchagua Valley wine tour ensure this itinerary is perfect for those with an affinity for the finer things in life.

Begin your trip in Buenos Aires, where dinner at the refined Fogón and a thrilling tango show promise to energize you for the exciting adventures ahead. Speaking of, jet to Ushuaia and get a feel for the city during a private walking tour before dedicating the next two days to nature-based excursions. First up is a scenic wildlife-watching cruise along the Beagle Channel, followed by a full-day off-roading adventure through the sub-Antarctic forests of Tierra del Fuego National Park. Continue to El Calafate afterward and spend an evening indulging in regional specialties at the exclusive Rancho Aparte restaurant. 

Your next two days in El Calafate will immerse you in the breathtaking landscapes of Los Glaciares National Park, explored by boat, on foot, on horseback, and by vehicle. Afterward, settle in for a scenic drive to the 5-star Explora Torres del Paine, and together with a hotel host, plan out how you'll spend the following days. Perhaps you'll journey by van between park highlights or lace up your hiking boots for a full-day trek up the towering Mirador Base Torres. Either way, you'll still be fizzing with excitement as you land in Santiago and end your adventure over a wine-tasting tour in Colchagua Valley. Learn more

Itinerary #4: Luxury Chilean Lake Crossing to Argentine Patagonia

Tailored for those seeking a deep yet leisurely exploration of Argentine Patagonia, this two-week excursion showcases breathtaking landscapes through finely selected activities. From the moment you arrive at Santiago's 5-star The Singular hotel to your farewell museum tour in Buenos Aires, every moment of this trip is filled with touches of luxury and beauty. Discover the magic of the Lake District's wildlife-filled islands, kayak on the glassy waters of López Bay, cruise around the fallen icebergs of Perito Moreno Glacier, and more.

Upon arrival in Santiago, your luxury escape gets off to a brilliant start, with a guided city tour on the agenda, followed by a Casablanca Valley wineries hopping excursion. Next, you're off to the charming Lake District city of Puerto Varas for a three-night stay at the lavish Hotel AWA. Spend your first night here getting acquainted with the town's peaceful tree-lined streets, then let a guide take the reins during an outing to the Chiloé Archipelago and throughout a thrilling helicopter and hiking tour. Afterward, settle in for a one-of-a-kind boat and bus trip, which brings you across the Lake District to Bariloche.

During your upscale three-day stay at Bariloche's Villa Beluno Hotel & Spa, embrace serene moments during a driving tour of the renowned Circuito Chico and a kayak and hiking adventure from López Bay. Next, fly to El Calafate for a series of exclusive excursions in Los Glaciares National Park. Begin with a scenic cruise to the majestic Perito Moreno Glacier, followed by an exhilarating 4WD journey through the expansive Patagonian steppe. Then, conclude your journey in Buenos Aires, sipping exceptional cocktails, savoring an elegant dinner and tango show, and hopping between fine museums. Learn more

Itinerary #5: Luxury Adventure in Argentine Patagonia

Delight in a speedy tour of Argentina's picturesque mountain towns and lesser-visited natural wonders on this luxury adventure. Three days of hiking from El Chaltén, a kayaking experience from Bariloche, and numerous day trips to ranches make this itinerary ideal for those eager to pack in active excursions. Meanwhile, nights at premier accommodations and a handful of upscale dinners ensure your creature comforts are never overlooked. 

Your luxury adventure begins in Buenos Aires, where a leisurely bike tour and a day at Estancia El Ombú effortlessly erase any lingering jet lag. The fun continues in Bariloche, thanks to welcome drinks at a local microbrewery, followed by a day of kayaking and hiking around the deep blue waters of Nahuel Huapi. Then, embark on a set of day trips, the first along the scenic Seven Lakes Road and the second to the dazzling Brazo Tristeza region, before setting your sights on El Calafate. Settle into your stay here with an exclusive closed-door dinner at the Rancho Aparte restaurant.

Refreshed and ready for more, spend the following two days exploring the diverse wonders of Los Glaciares National Park—from the awe-inspiring Perito Moreno Glacier to the historic elegance of Estancia Nibepo Aike. Next, transfer to El Chaltén, where three days of world-class hiking await. Kick things off with a relatively gentle trek up the Laguna Torre, then conquer a duo of challenging alpine trails between rejuvenating nights at the well-appointed Aguas Arriba lodge. Afterward, return to Buenos Aires and cap off your journey with a fantastic tango show and a privately guided city tour. Learn more

More Great 2-Week Patagonia Itineraries

Looking for more inspiration for your trip to Patagonia? Check out these other two-week Patagonia itineraries, with outdoor adventures, cultural trips, and best-of tours to hit the highlights.