Venice, Florence, Amalfi Coast & Rome - 10 Days

Day 1: Arrive in Rome, Train to Venice, Evening Walking Food Tour

Welcome to Italy! Arrive at one of Rome's two international airports, then transfer to the Roma Termini Station for a ride on the high-speed train en route to Venice. Once in the city, a water taxi will transport you to the town center and your hotel. Venice in northern Italy is famous for both industry and tourism. With nicknames like "Queen of the Adriatic," "City of Water," and "The Floating City," it's clear that the city's myriad canals are its main draw. Stretching across 117 small islands in the marshy Venetian Lagoon along the Adriatic Sea, the city has long been a commercial and cultural hub thanks to its strategic placement.

Depending on when you arrive, a great introduction to the city is to take a romantic cruise down Venice's canals on a historic gondola to see stunning architecture and narrow waterways. This is not a guided tour but rather a relaxing cruise that allows you to take in the amazing city from the water.

In the evening, head to the Cannaregio District, the site of the former Jewish Ghetto, for a walking food tour. The area is filled with restaurants and shops offering kosher Venetian specialties, a Jewish museum, and several tourist-friendly synagogues. Eat and drink your way through regional specialties as you learn about the Jewish and kosher influences and sample Cicchetti, creamy risottos, sweet pastries, and local wines. Buon appetito!

Day 2: Venice Walking Tour

Experience Venice's highlights with a guided walking tour. Start at Piazza San Marco, the heart of the city's cultural and administrative district. Tour Palazzo Ducale (Doge's Palace), a Venetian Gothic palace built as the primary residence for the Doge of Venice in 1340. The palace stands on St. Mark's Square, and its resplendent interior décor and priceless works of art make it a must-see for history and architecture buffs.

Adjacent to the palace is the San Marco's Basilica, originally the Doge's personal chapel. The building is one of the best surviving examples of Italo-Byzantine architecture and features a stunning collection of Byzantine art, gold mosaics, and exquisite marble floors.

The palace is also connected to the next-door prison by the infamous Bridge of Sighs, which has joined the two buildings since the 16th century. The bridge features a small window onto Venice's harbor and earned its grisly name from the prisoners' sighing as they got one last glimpse of the city on their way to execution. While most visitors gather outside the bridge to look in, you'll get the best sense of history from inside the bridge, looking out from the same window as the doomed medieval prisoners.

After the morning's tour, grab lunch at one of the city's many cafés before spending the afternoon exploring.

• Tour the 18th-century Chiesa di Santa Maria Assunta (also known as I Gesuiti) in the Cannaregio district and the Baroque 17th-century Basilica di Santa Maria della Salute, Venice's second most renowned church
• Ride the elevator to the top of the Campanile di San Marco for a bird's-eye view of Venice
• Dive into history at the Correr Civic Museum to see art and artifacts displays from Venice's history as well as the former royals' quarters
• Go shopping at the famous Rialto fish market, located at the heart of Venice. The smell of seafood and the sound of vendors vying for shoppers' attention make this colorful and hectic market a must-see for any Venice traveler 

In the evening, rent a bike and go for a relaxed bike ride around the city before finding the best bars and nightlife for a night out.

Day 3: Free Day in Venice

Today is a free day to explore Venice. Make the most of your time in the city with some of the following suggestions: 

• Discover art at the Ca' Pesaro Galleria Internazionale d'Arte Moderna, Peggy Guggenheim Collection Modern Art Museum, and La Biennale di Venezia Art Museum
• Explore San Giorgio Maggiore, one of Venice's smaller islands that stands separate from the main canals  
• See an opera show at the Teatro La Fenice 
• Haggle for produce at the busy Mestre market, held every Wednesday and Friday
• Go shopping for luxury items on Le Mercerie and Salizada San Moisè 
• Browse textiles, craft shops, unique boutiques, and galleries in the bohemian San Samuele district 
• Rent a kayak and explore Venice from the water 

Day 4: Train to Florence, Afternoon Food Tour

After breakfast, head to the train station to catch a train to Florence. Florence is Tuscany's regional capital and its most populous city. Long considered a cultural capital and the "Jewel of the Renaissance," Florence is home to many masterpieces of Renaissance art and architecture, including the iconic Duomo, a terracotta-tiled dome, and the Galleria dell'Accademia, which displays Michelangelo's "David" sculpture.

Spend the day exploring the top sites located in the medieval city center. Popular highlights include the sprawling 15th-century Pitti Palace and the world-famous Uffizi Gallery, which houses work by artists like Michelangelo and Leonardo da Vinci. As a center for art, Florence has hosted many of European history's most notable figures, including Botticelli, Donatello, Dante, Boccaccio, and Niccolò Machiavelli.

In the afternoon, indulge yourself in the decadence of Tuscany's culinary delights. A guided walking tour of the city led by a local is the perfect way to discover the region's history and find the best off-the-beaten-path gelato and coffee shops. Sample wares from city markets to find the best of the best. Try truffle panini, fresh-pressed Tuscan olive oil, and handmade chocolate focaccia, finished with a glass of chilled prosecco or Chianti wine.

Day 5: Day Trip to San Gimignano & Siena, Wine Tasting in the Chianti Classico

In the morning, head to the Tuscan countryside to explore the Chianti Region. Your first stop is the medieval village of San Gimignano, a UNESCO World Heritage Site located an hour away from Florence, which is famous for its Vernaccia wine and award-winning gelaterias. Explore the beautiful squares, palaces, and churches of the city before grabbing a coffee in an open-air café.

Continue to the Chianti Classico wine region to visit a typical Tuscan winery. The unique characteristics of the local climate have made the region unfavorable to most crops but ideal for growing wine grapes. Alternating fields of olive orchards and vineyards characterize this idyllic landscape. The Chianti wine, made primarily of Sangiovese grapes, is the local staple. Tour the cellars and vineyards, then enjoy a wine tasting accompanied by a delicious Tuscan lunch of pasta, cured meats, cheeses, and local desserts.

In the afternoon, visit nearby Siena, located a scenic hourlong drive away, to see the magnificent Cathedral, Torre del Mangia, and Town Hall, the site of the famous Palio horse race. Finish the day with a visit to the medieval fortress of Monteriggioni before returning to Florence for the night.

Day 6: Transfer to the Amalfi Coast, Positano Sunset Cruise

After breakfast at a sunny open-air café, head to the train station to take the train to Naples, then transfer to your hotel on the Amalfi Coast. This stretch of coastline south of Naples is renowned for its exceptional beauty and iconic medieval cliffside fishing villages. Lemon groves and sprawling summer villas cling to the steep cliffs that lead to sparkling blue water.

In the afternoon, venture onto the water with a sunset boat tour to Positano from Amalfi. With its steep houses tumbling down to the sea, old-timey hotels draped in flowering vines, and restaurant terraces, Positano is an obvious favorite with travelers looking for a getaway. Soak in the views of the coast and the Ionian Sea from the boat as you enjoy a glass of Prosecco and some light aperitifs. Swim or snorkel in the clear blue waters, or simply enjoy the view.

Disembark in Positano for a romantic dinner with ocean views. Enjoy a pasta dinner with fresh seafood paired with a glass of fruity Falanghina. Return to Amalfi for the night.

Day 7: Day Trip to Capri & Anacapri

Spend the day enjoying the sunshine, summer villas, and clear blue waters of Capri Island, known locally as the "pearl of the Mediterranean." Capri sits on the south side of the Gulf of Naples and is a popular destination. Ancient Romans used the island for summer villas for the Empire's rich and famous, while the Greeks called Capri the "Isle of Sirens."

In the morning, head out for a scenic drive along the Sorrentine coast to the Sorrento port, where you'll catch a hydrofoil to Capri. From here, go for a guided walking tour of the island's main attractions. See the main harbors (Marina Grande and Marina Piccola), walk along the Belvedere of Tragara (a villa-lined promenade with panoramic views), and explore the ruins of ancient Roman villas. Head up the hill to see Anacapri, the Piazzetta, and Augustus' Garden, as well as the best views of the Faraglioni Rocks.

In the afternoon, return to the water to explore the Grotta Azzurra, a naturally hollowed sea cave, and soak in the sunshine on the beach.

Day 8: Return to Rome, Afternoon Colosseum & Forum Tour

After a relaxing breakfast, it's time to say goodbye to the Amalfi Coast. Catch a high-speed train back to Rome, then check in to your hotel. According to legend, Rome was founded by brothers Romulus and Remus in 753 BCE atop Rome's Palatine Hill. The longtime center of the powerful Roman Empire, Rome boasts nearly 3,000 years of architecture, history, and culture. Visitors and locals wanting to soak in the sunshine flock to the beautiful Giardino degli Aranci, the city's vibrant orange tree gardens on Aventine Hill, or relax in the lush greenery of the Villa Borghese Gardens.

In the afternoon, dive into the history of the Roman Empire with a walking tour of the Colosseum, the world's largest amphitheater (tickets included). Walking through the ancient amphitheater is like taking a trip back in time to the days of the Roman Empire. Learn about some of ancient Rome's most famous and illustrious citizens, such as Julius Caesar, Emperors Augustus and Nero, and the Flavian Emperors who built the Colosseum.

From here, continue to the Roman Forum and Palatine Hill. Walk along the ancient Roman street Via Sacra to see the Temples of Vesta, Antonino, and Faustina. See the ancient Basilica Julia and Aemilia and experience the grandeur of the Roman Empire.

Day 9: Vatican Tour: Sistine Chapel & St. Peter's Basilica, Rome Walking Tour

Today you'll visit the Vatican City museums and Sistine Chapel, as well as other top sights, for an exclusive six-hour tour of the city's incredible art and history. Start at the Vatican, where you'll visit the Pio Clementio Museum, Gallery of the Candelabra, Gallery of Tapestries, and Gallery of the Geographical Maps. Continue to see the magnificent Raphael Rooms, ending in the breathtaking Sistine Chapel and St. Peter's Basilica. Experience the wonder of Renaissance art as you learn about the secret details and untold stories of the masterpieces.

Afterward, continue into the city for a tour of its most notable landmarks. Cross Piazza della Repubblica to see the Fountain of the Nyands, then continue to see the Trevi Fountain, La Colonna di Marco Aurelio, and the Palazzo di Montecitorio, which Bernini designed. Admire the exterior of the Pantheon and head inside for a look at the ancient Roman temple, then head to Palazzo Madama—the Senate seat—ending at Piazza Navona.

End your evening with a stroll to the neighborhood piazza for gelato and some people-watching.

Day 10: Depart Rome

Time to say goodbye to the country of love! After one last cappuccino over breakfast, head to the airport for your connecting flight home. Safe travels!

More Great Italy Itineraries

Looking for more inspiration for your trip to Italy? Check out these other Italy itineraries, explore different ways to spend 10 days in Italy, or discover the best time to visit Italy.